Prednisolone: use, contraindications
The drug "Prednisolone" is a syntheticThe agent, whose action is similar to the action of cortisone and hydrocortisone, produced by the adrenal cortex. He is 3-5 times more active than these hormones, but, unlike them, does not retain water and sodium in the body, does not increase the removal of potassium from the body.
This glucocorticosteroid is a white or yellowish powder that has no odor. It does not dissolve in water, it is very poorly soluble in chloroform, alcohol, methanol.
Treatment "Prednisolone" helps to get rid of allergic manifestations, exudative diathesis. It is used as an anti-shock, antitoxic, anti-inflammatory drug
The complex of hormones contained in Prednisolone,penetrating into skin cells (lymphocytes, fibroblasts, keratinocytes) reduce the synthesis of metabolic products and biologically active substances, inhibit the production of "extra" cells of the epidermis.
Why do I need Prednisolone? Its use is recommended for the treatment of collagen. Collagenosis is the combined name of diseases associated with the proliferation of blood vessels and connective tissues. "Prednisolone" is effective in bronchial asthma, rheumatic pain, inflammation of the joints. In the treatment of a malignant tumor of blood cells, which arises from the bone marrow, also can not do without the drug "Prednisolone." The use of the drug has proven itself in the treatment of mononucleosis, a disease associated with an increase in the liver and lymph nodes located on the palate. It is effective in the defeat of the skin of the nervous (neurodermatitis), neuro-allergic (eczema) or other character. Without "Prednisolon" can not do patients suffering from Addison's disease, in which the amount of hormones formed in the adrenal cortex is sharply reduced. Hemostatic anemia (decrease in hemoglobin of the blood), glomerulonephritis, affecting the kidneys, inflammation of the pancreas (pancreatitis) are also treated with the drug "Prednisolone". The use of the drug was justified for the normalization of shock or collapse states that occur against the backdrop of a sharp drop in pressure during surgical operations. "Prednisolone" is needed to reduce the reactions of rejection after organ transplantation.
In addition, this tool is widely used for the treatment of eye diseases: inflammation of the eyeball, conjunctivitis, inflammation of the cornea, injuries and operations performed on the eye.
"Prednisolone" is given in the form of injections fortreatment of sudden allergic reactions, removal from the state of shock, with an infarction. The same method is used for cirrhosis of the liver, renal or hepatic insufficiency, hepatitis, chemical poisoning.
In joint diseases, the drug is injected directly into the joints.
Tablets are used to treat less acutestates: all types of connective tissue diseases, arthritis, lymphogranulomatosis, lung diseases, kidney, gastrointestinal tract, hepatitis, enteritis and a number of other diseases.
For the treatment of urticaria, neurodermatitis, eczema and many other skin diseases, it is recommended to use "Prednisolone" as an ointment.
However, do not forget that this remedy, like any medications, can have contraindications. The hormonal drug can not be taken sick
- diabetes mellitus
- Iscenko-Cushing's disease
- diabetes mellitus
- gastric ulcer
"Prednisolone", which application is designed for the treatment of such a wide spectrum of disease, has several dosage forms:
- tablets from 0.001 to 0.05 g of active ingredient in each. Usually sold in packs of 100 pieces.
- Ampoules with a suspension intended for injection. May contain 25,30,50 mg of active ingredient.
- Ointment 0.5%
- Eye suspension 0.5%
Any kind of medicine "Prednisolone" can be used only on the advice of a doctor.